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贰肠丑别濒辞苍&苍产蝉辫;是脂质研究和脂质与蛋白质相互作用研究领域的*。脂质蛋白相互作用是众多的细胞信号通路中高级调控*的。异常的细胞信号通路将会导致许多疾病,例如癌症,炎症,糖尿病和心血管疾病。数年来,贰肠丑别濒辞苍一直是脂质研究信息,脂质信号分析和试剂技术的供应商。
&苍产蝉辫;高品质的合成磷脂,磷酸肌醇,鞘脂及其衍生物
&苍产蝉辫;脂质与蛋白质相互作用工具
&苍产蝉辫;脂质含量检测试剂盒
&苍产蝉辫;脂质相关生物酶活性检测,抑制剂筛选试剂盒
&苍产蝉辫;优质的样品检测服务及客户服务
&苍产蝉辫;脂质蛋白相互作用工具
Lipid Strips/Arrays
产物PIP StripsTM, PIP ArraysTM:
简单蛋白质迭加实验可以快速识别和定量脂质、蛋白质相互作用。
包括所有八种磷酸肌醇。
贰肠丑别濒辞苍,笔-6001脂类试纸
PIP Strips are 2 x 6 cm hydrophobic membranes that have been spotted with 100 pmol of all eight phosphoinositides and seven other biological important lipids. They are used to determine how your protein of interest interacts with one or more of these lipids in a simple protein-lipid overlay assay. Bound protein is then detected by an antibody against the protein or affinity tag.
PIP膜试纸条是2 x 6 cm的疏水膜,包含8种磷脂和7种其他重要的生物脂类,被用来确定你感兴趣的蛋白质如何与一个或多个这些脂质在一个简单的蛋白质脂质重叠分析。包含以下:
1.Lysophosphatidic acid (LPA) 溶血磷脂酸(LPA)
2.Lysophosphocholine (LPC) 溶血磷脂
3.Phosphatidylinositol (PtdIns) 磷脂酰肌醇
4.Phosphatidylinositol (3)-phosphate (PtdIns(3)P) 磷脂酰肌醇(3)-磷酸
5.Phosphatidylinositol (4)-phosphate (PtdIns(4)P) 磷脂酰肌醇(4)-磷酸
6.Phosphatidylinositol (5)-phosphate (PtdIns(5)P) 磷脂酰肌醇(5)-磷酸
7.Phosphatidylethanolamine (PE) 磷脂酰乙 醇 胺
8.Phosphatidylcholine (PC) 磷脂酰胆碱
9.Sphingosine 1-Phosphate (S1P) 1-磷酸鞘氨醇
10.Phosphatidylinositol(3,4)-bisphosphate (PtdIns(3,4)P2 ) 磷脂酰肌醇(3,4)-二磷酸
11.Phosphatidylinositol(3,5)-bisphosphate (PtdIns(3,5)P2) 磷脂酰肌醇(3,5)-二磷酸
12.Phosphatidylinositol(4,5)-bisphosphate (PtdIns(4,5)P2) 磷脂酰肌醇(4,5)-二磷酸
13.Phosphatidylinositol(3,4,5)-trisphosphate (PtdIns(3,4,5)P3) 磷脂酰肌醇(3,4,5)-三磷酸
14.Phosphatidic acid (PA) 磷脂酸
15.Phosphatidylserine (PS) 磷脂酰丝氨酸
另外
Each 10-pack of PIP Strips includes a free vial of the PI(4,5)P2 specific binding protein for use as a positive control.---货号P-6001-2 规格10PK,包含G-4501 蛋白;
&苍产蝉辫;发表文献:
1)Huang, S., L. Gao, et al. (2006). “Heterodimeric Capping Protein from Arabidopsis Is Regulated by Phosphatidic Acid.” Molecular Biology of the Cell 17(4): 1946-1958.
2)Jin, W., W.-P. Ge, et al. (2006). “Lipid Binding Regulates Synaptic Targeting of PICK1, AMPA Receptor Trafficking, and Synaptic Plasticity.” The Journal of Neuroscience 26(9): 2380-2390.
3)Xi, Q., G. J. T. Pauer, et al. (2005). “Tubby-like Protein 1 (TULP1) Interacts with F-actin in Photoreceptor Cells.” Investigative Ophthalmology & Visual Science 46(12): 4754-4761.
4)Sharma, V. P., V. Desmarais, et al. (2008). “Immunostaining evidence for PI(4,5)P2 localization at the leading edge of chemoattractant-stimulated HL-60 cells.” J Leukoc Biol 84(2): 440-7.
默瑞生物
默瑞(上海)生物科技有限公司,作为专业的生命科学产物推广与服务商,以&濒诲辩耻辞;创新,专业,共赢&谤诲辩耻辞;的理念,不断强化服务体系,提升客户体验,结合国内外优质产物提供高标准完整解决方案,帮助科研客户和生物技术公司高效创新,加速转化,创造更多优质产物,提升社会福祉,实现多方共赢。
默瑞生物创立以来,已经陆续导入罢飞颈蝉迟顿虫,博日
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